Monitoring of a Broad Set of Pharmaceuticals in Wastewaters by High-Resolution Mass Spectrometry and Evaluation of Heterogenous Catalytic Ozonation for Their Removal in a Pre-Industrial Level Unit

The removal of contaminants emerging concern (CECs) occurring in wastewater effluents, such as pharmaceutically active substances (PhACs) and personal care products, pose a big research challenge since they can be major source pollution for water bodies danger to public health. objective this work was perform comprehensive monitoring broad set PhACs (>130) treatment plant (WWTP) close Thessaloniki (Greece), well evaluate the potential heterogeneous catalytic ozonation CECs from through continuous flow system. high-resolution mass spectrometry analysis revealed highest average concentrations irbesartan (1817 ng/L). Antihypertensives along with antibiotics, psychiatrics, β-blockers were found aggravate effluents. Removal efficiency after conventional >30%. results unit operation indicate that introduction proper solid material acts catalyst enhance CECs. A preliminary risk assessment using quotient (RQ) telmisartan entail high acute risk. overall underline urgent need incessantly monitor expand toxicological studies establish sublethal chronic effects on aquatic organisms.